|| Associate Professor
||University of Chicago, 2003
Academic Editor, PLoS One
Guest Associate Editor, Frontiers in Decision Neuroscience
(Special Topic: Dopamine and behavioral flexibility)
Society for Neuroscience
American Psychological Association
The lab focuses on mechanisms of neuroplasticity and learning in the basal ganglia using mouse genetic models and techniques with an emphasis on reinforcement learning and models. Applied areas of interest include addiction, Parkinson's disease and obesity.
Beeler, J.A., Jakowec, M., Petzinger, G. (in press). The enemy within: propagation of aberrant corticostriatal plasticity to cortical function in Parkinson's disease. Invited review, Frontiers in Neurology.
Petzinger, G.M., Fisher, B.E., McEwen, S., Beeler, J.A., Walsh, J.P., and Jakowec, M.W. (2013). Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease. Lancet Neurol 12, 716–726.
Beeler, J.A., McDaid, J, Frank, MJ, Alexander, E., Turkson, S., Bernandez, M.S., McGehee, D.S. and Zhuang, X. (2012). A role for dopamine-mediated learning in the pathophysiology and treatment of Parkinson’s disease. Cell Reports, v2(6), p 1747. DOI: 10.1016/j.celrep.2012.11.014.
Beeler, J.A. (2012). Thorndike 2.0: Dopamine and the regulation of thrift. Invited Focused Review, Frontiers in Behavioral Neuroscience, Front. Neurosci. DOI: doi:10.3389/fnins.2012.00116.
Beeler, J.A., Frazier, C.R.M., Zhuang, X. (2012). Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources. Frontiers in Integrative Neuroscience, v. 6:49. DOI: 10.3389/fnint.2012.00049
Beeler, J.A., McCutcheon, J.E., Cao, Z.F.H., Murakam, M., Roitman, M.F., Zhuang, X. (2012). Taste uncoupled from nutrition fails to sustain reinforcing properties of food, European Journal of Neuroscience, epub ahead of print. DOI: 10.1111/j.1460-9568.2012.08167.x
Beeler, J.A., Frazier, C.R.M., Zhuang, X. (2012). Dopaminergic enhancement of local food seeking is under global homeostatic control. European Journal of Neuroscience, v 35, pp.146-159.